JCI - C/EBPε mediates nicotinamide-enhanced clearance of Staphylococcus aureus in mice
نویسندگان
چکیده
Division of Pediatric Infectious Diseases and The Research Division of Immunology, Department of Biomedical Sciences, and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA. Department of Pediatrics, David Geffen School of Medicine, UCLA, Los Angeles, California, USA. Division of Hematology and Oncology, Cedars-Sinai Medical Center, UCLA School of Medicine, Los Angeles, California, USA. Department of Medicine A, Hematology, Oncology and Pneumology, University of Muenster, Muenster, Germany. Division of Infectious Diseases, Cedars-Sinai Medical Center, Los Angeles, California, USA. Linus Pauling Institute, Department of Biochemistry and Biophysics, Oregon State University, Corvallis, Oregon, USA. National Cancer Institute of Singapore, National University, Singapore.
منابع مشابه
C/EBPε mediates nicotinamide-enhanced clearance of Staphylococcus aureus in mice.
The myeloid-specific transcription factor, CCAAT/enhancer-binding protein ε (C/EBPε) is a critical mediator of myelopoiesis. Mutation of this gene is responsible for neutrophil-specific granule deficiency in humans, a condition that confers susceptibility to Staphylococcus aureus infection. We found that C/EBPε-deficient mice are severely affected by infection with S. aureus, and C/EBPε deficie...
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